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Research Interests

  • Computational biology and bioinformatics

  • LncRNA identification and functional study

  • DNA methylation biomarkers in cancers and diseases

  • Noninvasive prenatal/cancer testing using plasma DNA analysis

  • Data mining and visualization

Research Highlights

Size-tagged preferred ends showed utility in noninvasive prenatal testing and explained the shortness of fetal DNA

Trace the tissue origin of the tumor though liquid biopsy

Extra-fast and accurate lncRNA classification

Identification and functional annotation of Linc-Yy1 gene

Functional annotation of Yy1 transcription factor during myogenesis

Research Experiences

Research Assistant Professor, The Chinese University of Hong Kong,

2017-current

Postdoctoral fellow, The Chinese University of Hong Kong,

2014-2017

Doctoral thesis, The Chinese Unviersity of Hong Kong,

2010-2014

  • I have participated in many biological, clinical and computational projects. I have analyzed a large amount of NGS data using ChIP-seq, RNA-seq and BS-seq technology and published several bioinformatics software in DNA methylation and lincRNA field.

  • I have participated in writing grant proposals for HKRGC and NSFC with Prof. Hao SunProf. Huating Wang, and Prof. Zhengguo Wu (HKUST).

Bachelor thesis, Unviersity of Science and Techonology of China,

2006-2010

  • National Students Innovative Project: Gesture interaction methods: an implementation based on FPGA, wireless EMG sensors and accelerometers. Under supervision of Prof. Xiang Chen, I have designed and implemented an integrated system for electromyography signal capture and recognition.

  • ABU Robocon 2010 (China Division) USTC team supervised by Prof. Fanrang Kong and Prof. Hui Li. I was the leader of the electronic circuit team. I have designed and implemented most of the PCBs used on our robots.

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